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What is a Chromosome? A chromosome is a long, continuous strand of DNA that contains many genes. Genes function as the basic unit of heredity in living cells, coding for various proteins. Each gene is located at a specific position on the chromosome, known as its locus. Chromosomes also contain non-coding regions of DNA, which […]

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In prokaryotic cells the focus of the regulation of gene expression is almost entirely at the level of the initiation of transcription. However, in eukaryotic cells, regulation of gene expression can occur at all stages of transcription and translation, and even at protein stability. Opportunities for Gene Regulation in Gene Expression in Eukaryotes Those common […]

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Anti-Termination It is possible for prokaryotic RNA polymerase to ignore termination signals and continue to transcribe until a downstream termination signal is reached. This mechanism is used by lambda phage. The lambda N gene codes for pN which interacts with polymerase RNA to enable it to read through to genes further downstream. Another antiterminator called […]

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Gene Regulation at Transcriptional Termination In the previous article we saw how RNA polymerase determines how to start transcription. In this article, we will examine how it decides to end transcription. Before we dive in, however, let’s take some time to remind ourselves of the lay of the land. So far, we are well familiar […]

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Prokaryotes are able to regulate gene expression by applying unique tricks in their toolbox. In prokaryotic cells, genes expression is regulated almost entirely at the level of the initiation of transcription. In eukaryotic cells, regulation of gene expression can occur at all stages of transcription and translation, and even after a protein is made. I […]

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In the next series of articles I will be covering transcription in prokaryotes. I suppose that this is a topic that you have been introduced to in previous biology classes that you have taken. We will get a more in-depth look into the subject. However, before we dive in, let’s review a few basic concepts. […]

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